Improving the sensitivity of NIR spectroscopy with an enrichment technique: Determining a trace analyte of ethyl carbamate

Abstract

An exploration was made to develop a determination method of a low-concentration analyte by NIR spectroscopy. An absorber, silica gel was employed to extract and enrich a low-concentration analyte of ethyl carbamate. The solid absorber with the enriched analyte was measured by NIR spectroscopy in the range of 800-2500 nm. Afterwards, PLS regression was performed between the NIR spectra and the concentrations of the analyte for quantitative analysis of the low-concentration analyte. The spectra of 20 solid samples of analyte-absorbed silica gel showed a good correlation with the concentrations of ethyl carbamate in the samples. A leave-one-out cross validation was applied to evaluate the prediction ability of PLS models built with the full spectra, spectra in the region of 1920-1970 nm and the region of 2250-2430 nm, respectively. The values of the root-mean-square error of the cross validation (RMSECV) were about 0.1 mg L-1 (0.1 ppm). 2007 © The Japan Society for Analytical Chemistry.