GABA and sleep: Molecular, functional and clinical aspects

Abstract

Focuses on the neuropsychopharmacology of GABA and its role in sleep and wakefulnessPresents neurochemical, electrophysiological, and neuropharmacological approaches to understand GABAergic mechanismsOffers an overview of current approaches and medicationsFeatures contributing authors who are leading experts in the field of sleep and neuropharmacologyGABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. This book brings together many of the world's leading investigators to discuss current and anticipated developments in the areas of geriatric sleep medicine and provides a comprehensive examination of current principles and practice in this field. It is divided into three main sections: Section I: Basic Physiology and Pharmacology Section II: Sleep Science and Circuitry Section III: Neurotherapeutics The areas covered include findings from research investigations various aspects of GABAergic systems and the regulation of sleep. The book is suitable for basic and clinical neuropharmacologists, sleep researchers, psychiatrists, sleep disorders specialists, clinicians, medical students, and all professionals interested in the interdisciplinary areas of sleep and neuropharmacology.