Solid-Phase Synthesis of Oligourea Peptidomimetics

  • Boeijen A
  • Liskamp R
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Abstract

A procedure for the solid-phase synthesis of oligourea peptidomimetics starting from Boc-protected monomers is described. The compounds are prepared on Tentagel(R) resin and can be obtained selectively either as the C-terminal free acids with UV irradiation when a photocleavable Linker is used or as C-terminal hydantoins with 10% TEA/MeOH and a catalytic amount of KCN.

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APA

Boeijen, A., & Liskamp, R. M. J. (1999). Solid-Phase Synthesis of Oligourea Peptidomimetics. European Journal of Organic Chemistry, 1999(9), 2127–2135. https://doi.org/10.1002/(sici)1099-0690(199909)1999:9<2127::aid-ejoc2127>3.0.co;2-t

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