Streptococcal pharyngitis in a Child, Complicated with a Necrotizing Myositis: Diagnosis, Management and Follow-Up

Abstract

Patient: Male, 2.5-year-old Final Diagnosis: Necrotising myositis Symptoms: Fever Clinical Procedure: Surgical exploration, resection of necrotic tissue Specialty: Infectious Diseases • Surgery Objective: Rare disease Background: Group A streptococcus is a common cause of pharyngitis and can also cause a wide variety of invasive infec-tions, including necrotizing soft-tissue infections. The presented case is one of the rare occurrences of necro-tizing soft-tissue infection as a consequence of hematogenous spread and is the first described pediatric case of streptococcal myositis that was clearly preceded by pharyngitis. Case Report: A 2.5-year-old boy, previously healthy, fell ill 3 days before admission with high-grade fever, diffuse erythem-atous truncal rash and, later, with pain in the left lower leg. The next day, scarlet fever was diagnosed, and he was started on oral penicillin V. In the following 2 days, the fever and pain in the leg did not subside; edema and redness of the left shin appeared. On admission, he was febrile and had tachycardia, and the mouth ex-amination was consistent with bacterial pharyngitis. The left shin was grossly edematous, with diffuse bluish skin discoloration. Empiric antibiotic treatment with benzylpenicillin and clindamycin was started. An ultrasound scan of the left shin revealed extensive myonecrosis. Urgent fasciotomy was done, and necrotic muscles were surgically excised. Conclusions: Streptococcal necrotizing myositis is exceedingly rare. Due to potentially life-threatening complications and a need for urgent surgical intervention, clinicians must have a low threshold of suspicion, even in atypical patho-genesis and presentation.