Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data.
Huang, J., Eilbeck, K., Smith, B., Blake, J. A., Dou, D., Huang, W., … Tan, M. (2016). The development of non-coding RNA ontology. International Journal of Data Mining and Bioinformatics, 15(3), 214–232. https://doi.org/10.1504/IJDMB.2016.077072