Impact of Metabolic Syndrome Components on Asthma Control and Life Quality of Patients

Abstract

The purpose of this study was to assess the characteristics of the clinical course of asthma in patients with metabolic syndrome (MetS) and to analyze the influence of the MetS components on the course of asthma, control of asthma symptoms, and the the quality of life (QL) of patients with asthma. Materials and Methods: We examined 95 asthma patients aged from 18 to 60 years. The patients were divided into 2 groups. Group 1 included 35 patients without MetS (24/68.6% women and 11/31.4% men; mean age, 49.81 +/- 0.77 years), and Group 2 included 60 patients with MetS (45/75.0% women and 15/25.0% men: mean age, 49.82 +/- 0.77 years). The asthma diagnosis was based on the integral assessment of symptoms. medical history. health status. and spirometry values according to the Global Strategy for Asthma Management and Prevention (2017). MetS was diagnosed according to the IDF consensus criteria (2006). Results: The MetS components. such as central obesity. high blood pressure. dyslipidemia, carbohydrate metabolism disorder. cause a more serious and unfavorable course of asthma, with frequent exacerbations, calls to emergency service and hospital admissions, severe asthma symptoms. uncontrolled asthma symptoms, low spirometry results, and low level of QL in the physical and psychological domains.