Shedding light on a new treatment for diabetic wound healing: A review on phototherapy

80Citations
Citations of this article
178Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Impaired wound healing is a common complication associated with diabetes with complex pathophysiological underlying mechanisms and often necessitates amputation. With the advancement in laser technology, irradiation of these wounds with low-intensity laser irradiation (LILI) or phototherapy, has shown a vast improvement in wound healing. At the correct laser parameters, LILI has shown to increase migration, viability, and proliferation of diabetic cells in vitro; there is a stimulatory effect on the mitochondria with a resulting increase in adenosine triphosphate (ATP). In addition, LILI also has an anti-inflammatory and protective effect on these cells. In light of the ever present threat of diabetic foot ulcers, infection, and amputation, new improved therapies and the fortification of wound healing research deserves better prioritization. In this review we look at the complications associated with diabetic wound healing and the effect of laser irradiation both in vitro and in vivo in diabetic wound healing. © 2014 Nicolette N. Houreld.

Cite

CITATION STYLE

APA

Houreld, N. N. (2014). Shedding light on a new treatment for diabetic wound healing: A review on phototherapy. The Scientific World Journal. https://doi.org/10.1155/2014/398412

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free