Lupus nephritis in pregnancy; a mini-review to current knowledge

Abstract

Systemic lupus erythematosus (SLE) is an auto-immune disease with the highest incidence in women of reproductive age. Recent studies indicate an increased rate of lupus flare during pregnancy. One main cause of death in lupus patients is renal involvement that is manifested as lupus nephritis. Active lupus nephritis is the biggest threat to pregnancy outcome in women with lupus. Consultation with a nephrologist, rheumatologist and perinatologist is recommended in order to carry a successful pregnancy to term.