InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
Ranganathan, R., & Ross, E. M. (1997, December 1). PDZ domain proteins: Scaffolds for signaling complexes. Current Biology. Cell Press. https://doi.org/10.1016/s0960-9822(06)00401-5