Total synthesis of the presumed amphidinolide A

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Abstract

Judicious use of both inter- and intramolecular Stille reactions was required in the synthesis of 1, the putative stereostructure of amphidinolide A. Compound 1 was shown to be a diastereomer of the natural product.

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Lam, H. W., & Pattenden, G. (2002). Total synthesis of the presumed amphidinolide A. Angewandte Chemie - International Edition, 41(3), 508–511. https://doi.org/10.1002/1521-3773(20020201)41:3<508::AID-ANIE508>3.0.CO;2-7

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