Automatic drug delivery system for the drug adrenaline using Pi, Pid, Imc & Mpc controllers

Abstract

Continuous specialist care and controlling of Mean Arterial Blood Pressure (MABP) of the patients for the period of postoperative cardiac surgery is the most problematic task for the medical personnel. Drug adrenaline is used to normalize the low blood pressure of the patients to the preferred level and manual control of the drug infusion rate of the patients may also be a challenging one. To mitigate this problem an automatic drug delivery system is designed, particularly if it is adjusted to the deviations in the patient’s model. The main objective of this paper is to control the MABP by injecting the drug adrenaline automatically into the patient’s body using four different control schemes such as PI, PID, IMC, and MPC controllers. These controllers effectively control the blood pressure of the patients to the preferred level and carry out strongly in the occurrence of deviations in the patient response. The efficiency of the proposed work is assessed by the simulation for the purpose of an automatic drug delivery scheme to control the MABP.