Clinicopathological Study of Intraoperative Radiotherapy in Brain Tumor

Abstract

We conducted intraoperative radiotherapy using Linac 12 MeV electron in the amount of 3,000 rads to a 42-year-old male sufferring from a malignant tumor of right occipital lobe, and Linac 12 MeV electron 2,000 rads to a 62-year-old male afflicted with a left frontal lobe tumor. The effect of acute stadium of radiotherapy for malignant brain tumor was bleeding, hyperemia interstitial swelling and degeneration of the vascular wall. In the delayed radiation necrosis, hyaline degeneration of the vascular wall and thrombosis reported in literatures. The vascular changes in the acute stadium of radiotherapy is considered to be correlated with the incidence of the delayed radiation necrosis. © 1978, The Japan Neurosurgical Society. All rights reserved.