Fecal Calprotectin During Treatment of Severe Infantile Colic With Lactobacillus reuteri DSM 17938: A Randomized, Double-Blind, Placebo-Controlled Trial

Abstract

Fecal calprotectin level has been reported to correlate with inflammation in inflammatory bowel disease in adults, and recently its relationship with infantile colic has also been described. Fecal calprotectin is elevated in infants with hematochezia and possible allergic colitis. The objectives were to evaluate fecal calprotectin at the time of enrollment and its variation after 3 weeks of therapy with a probiotic ( Lactobacillus reuteri DSM 17938) in infants with severe infantile colic admitted to our hospital for either hematochezia, …