Abstract
Several acid addition salts of amino ester derivatives of 3‐oxy‐substituted 1,4‐benzodiazepines were prepared and tested for water solubility, stability, and pH. The monomethanesulfonic acid salts were the most suitable for parenteral administration. Copyright © 1974 Wiley‐Liss, Inc., A Wiley Company
Author supplied keywords
- 1,4‐Benzodiazepines, 3‐oxy‐substituted—water‐soluble derivatives synthesized and tested for water solubility, stability, and pH
- Acid salts—synthesis of water‐soluble derivatives of 3‐oxy‐substituted 1,4‐benzodiazepines, tested for water solubility, stability, and pH
- Lorazepam—synthesis of aminoacetyl derivatives, tested for water solubility, stability, and pH
- Oxazepam—synthesis of aminoacetyl derivatives, tested for water solubility, stability, and pH
Cite
CITATION STYLE
APA
Nudelman, A., McCaully, R. J., & Bell, S. C. (1974). Water‐soluble derivatives of 3‐oxy‐substituted 1,4‐benzodiazepines. Journal of Pharmaceutical Sciences, 63(12), 1880–1885. https://doi.org/10.1002/jps.2600631211
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