Comparative Sedation with Sevoflurane and Thiopental in Children Undergoing MR Imaging

Abstract

Objective: To compare the use of propofol and thiopental in children undergoing MRI. Study Design: Descriptive, comparative study. Place and Duration of Study: University of Health Sciences, Van Training and Research Hospital, Van, Turkey, between January 01 and December 31, 2019. Methodology: One thousand two hundred and twenty two paediatric patients having MRI were included and divided into two groups. Patients aged 2-18 years who were administered Propofol were classified as Group I, and the patients under the age of 2 years who were administered Thiopental were classified as group II. All patients received Sevoflurane insufflation via face mask after induction agent. Patient’s demographic data, ASA scores, anaesthesia-procedure-recovery times, comorbidities, type of MRI examination and complications were recorded. Results: Age, body weight and ASA score of the patients in Group I were higher than Group II (p<0.05). Epilepsy, cerebral palsy, mental retardation, speech retardation and autism were more prevalent in Group I than in Group II (p<0.05). Neuromuscular growth retardation, hydrocephalus, and metabolic disease were less common in Group I than in Group II (p<0.05). With this Apnea and desaturation was higher in Group I, and bradycardia was higher in Group II. Conclusion: Sevoflurane insufflation with a face mask can be safely used in children after induction of anaesthesia with propofol or thiopental.