Anticancer activity of cissus quadrangularis l. Methanolic extract against MG63 Human osteosarcoma cells – an in-vitro evaluation using cytotoxicity assay

Abstract

To evaluate the anticancer effects of Cissus quadrangularis leaf extract against MG63 cells. MG63 cells were obtained from NCCS, Pune. The methanolic extract of Cissus quadrangularis was prepared and its anticancer activity was tested in cell lines using Mossman method of cytotoxicity assay. The cell viability of MG63 cells ranged between 29.65% and 73.59% at an extract concentration from 1000µg/ml to 7.8µg/ml. The IC50 of extract revealed by this cytotoxicity assay was around 100 µg/ml. This study showed anticancerous activity of C.quadrangularis leaf extract against MG63 cells, which can be further characterized by future studies and aid in treatment of bone tumors.