Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades

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Abstract

p Conclusion/Significance: Fucoidan exerts its anti-tumor function by modulating ER stress cascades. Contribution of ER stress to the fucoidan-induced cell apoptosis augments our understanding of the molecular mechanisms underlying its antitumour activity and provides evidence for the therapeutic application of fucoidan in cancer.

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Chen, S., Zhao, Y., Zhang, Y., & Zhang, D. (2014). Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades. PLoS ONE, 9(9). https://doi.org/10.1371/journal.pone.0108157

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