Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades

Abstract

p Conclusion/Significance: Fucoidan exerts its anti-tumor function by modulating ER stress cascades. Contribution of ER stress to the fucoidan-induced cell apoptosis augments our understanding of the molecular mechanisms underlying its antitumour activity and provides evidence for the therapeutic application of fucoidan in cancer.