Heart failure due to cytomegalovirus myocarditis in immunocompetent young adults: A case report

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Background: Cardiac complications constitute a rare clinical manifestation of cytomegalovirus (CMV) infection. This virus is usually asymptomatic in immunocompetent individuals. We report a case of myocarditis and cardiac insufficiency due to primary CMV infection. Serological tests by using ELISA method showed positive results for the virus. Case presentation: A 41-year-old man with no prior comorbidities presenting with dyspnoea, fever, and oedema was admitted to the cardiac emergency service. He had fever and dry cough, which aggravated into progressive respiratory distress, lower limb oedema, and orthopnoea 30 days prior to hospitalisation. The electrocardiogram revealed sinus tachycardia, first-degree right bundle branch block, and ventricular and left atrial overload as well as diffuse and nonspecific disturbances of ventricular repolarization. Serological tests were conducted, and IgM (1.54 UI/mL) and IgG (2.5 UI/mL) were found positive only for CMV by using ELISA. The patient was diagnosed with cardiac insufficiency due to CMV myocarditis. He was treated with ganciclovir for 10 days and received supportive medication. Conclusion: This case reaffirms the possibility of cardiac involvement in CMV infection and emphasises the importance of viral aetiologies as differential diagnoses for acute myocarditis.




Magno Palmeira, M., Umemura Ribeiro, H. Y., Garcia Lira, Y., Machado Jucá Neto, F. O., Da Silva Rodrigues, I. A., Fernandes Da Paz, L. N., & Nascimento Pinheiro, M. D. C. (2016). Heart failure due to cytomegalovirus myocarditis in immunocompetent young adults: A case report. BMC Research Notes, 9(1). https://doi.org/10.1186/s13104-016-2181-5

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