Cephabacins, new cephem antibiotics of bacterial origin iii. structural determination

Abstract

The structures of 15 new cephem antibiotics, cephabacin F1~9 and H1~6, were determined by their spectroscopic analyses and decomposition studies. They are consisted of a cephalosporin nucleus and a di, tri or tetrapeptide including a new amino acid which is bound at the position 3 with an ester bond. The components, F1~9, showed unique biological activities by the presence of a formylamino group at the position 7. © 1984, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.