Quorum Sensing Inhibitors: The Novel Bacterial Infection Disrupting Agents

Abstract

With increasing misuse of antimicrobial substances in medical settings, it became imminent to search for alternative pathogen control means to aid in preventing disease spread. Among such alternatives is the action upon virulent gene expression of the pathogen itself. A possible approach in this direction is the search for quorum sensing inhibitors from different components of the environment. In the last decade, a great interest in the search for new and novel anti-quorum sensing substances from plant and microbial origin has been observed. In this review, we are trying to follow up what has been published in this direction showing areas of interest for researchers to follow.