ACE and ACE2: Their role to balance the expression of angiotensin II and angiotensin-(1-7)

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Abstract

The discovery of angiotensin-converting enzyme 2 (ACE-2) has revealed a far more complex enzymatic cascade that may influence the renin-angiotensin system within the kidney, specifically the expression of the functional products angiotensin II (Ang II) and Ang-(1-7). The regulation of this critical system involved in blood pressure control must now encompass the integral relationship of ACE and ACE-2 activities. © 2006 International Society of Nephrology.

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Chappel, M. C., & Ferrario, C. M. (2006, July 12). ACE and ACE2: Their role to balance the expression of angiotensin II and angiotensin-(1-7). Kidney International. Nature Publishing Group. https://doi.org/10.1038/sj.ki.5000321

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