1067 SOCIODEMOGRAPHICS, POOR OVERALL HEALTH, CARDIOVASCULAR DISEASE, DEPRESSION, FATIGUE, AND DAYTIME SLEEPINESS ASSOCIATED WITH SOCIAL JETLAG INDEPENDENT OF SLEEP DURATION AND INSOMNIA

Abstract

Introduction:Social jetlag (difference between weekday and weekend sleep midpoint) has emerged as an important circadian marker for health outcomes. Previous studies, though, have rarely focused on general population samples and may be confounded with short sleep and insomnia.Methods:Data from the Sleep and Healthy Activity, Diet, Environment, and Socialization (SHADES) Study was used. SHADES is a community-based survey of N=1,007 adults age 22–60. Social jetlag was assessed using the Sleep Timing Questionnaire and was calculated by subtracting weekday from weekend sleep midpoint and was represented in hours. N=984 respondents provided complete data. sleep duration was assessed with the NHANES item, and insomnia was assessed with the Insomnia Severity Index[ISI]. Covariates included age, sex, race/ethnicity, education, employment, income, sleep duration (measured using the NHANES item), and insomnia (measured with the Insomnia Severity Index[ISI]. Overall health was self-reported as “Excellent,” “Good,” or “Fair/Poor.” Cardiovascular disease was assessed as history of any condition. Depression was measured with the Patient Health Questionnaire[PHQ], fatigue with the Fatigue Severity Scale[FSS], and sleepiness with the Epworth Sleepiness Scale[ESS]. Regression models, adjusted for all covariates, examined whether social jetlag predicted any of these outcomes.Results:Greater social jetlag was seen among high-school graduates (B=25.9mins,p<0.05) vs college graduates, and fewer minutes of social jetlag was seen among Blacks/African-Americans (B=-17.9mins,p<0.05), those in the poorest income quintile vs the highest (B=-22.9mins,p<0.05), unemployed (B=-19.0mins,p<0.05). Each ISI point was associated with -2.0 social jetlag minutes (p<0.01), and each hour of sleep was associated with -6.6 minutes (p<0.01). Adjusted for covariates, each hour of social jetlag was associated with a 22.1% and 28.3% increased likelihood of good and fair/poor health, respectively (vs excellent) (p<0.01). Each hour was associated with an 11.1% increased likelihood of heart disease (p<0.05). Additionally, each hour was associated with 0.25 PHQ points, 0.19 ESS points, and 0.56 FSS points (p<0.05).Conclusion:Social jetlag in a community sample is associated with race/ethnicity, income, education, employment, sleep duration, and insomnia. Adjusting for these, social jetlag is associated with poorer health, heart disease, worse mood, and increased sleepiness and fatigue.Support (If Any):K23HL110216 and R21ES022931