This Technical Note presents the direct surface modification of a glass/PTFE hybrid microfluidic chip, via radio frequency glow discharge plasma polymerisation of tetraethlylene glycol dimethylether (tetraglyme), to produce hydrophilic, non-fouling, PEO-like surfaces. We use several techniques including X-ray photoelectron spectroscopy (XPS), direct enzyme-linked immunosorbent assays (ELISA) and immunofluorescent imaging to investigate the channel coatings. Our results indicate the successful deposition of a PEO-like coating onto microchannel surfaces that has both solution and shelf stability (>3 months) and is capable of preventing fibrinogen adsorption to the microchannel surfaces. © The Royal Society of Chemistry.
CITATION STYLE
Salim, M., Mishra, G., Fowler, G. J. S., O’Sullivan, B., Wright, P. C., & McArthur, S. L. (2007). Non-fouling microfluidic chip produced by radio frequency tetraglyme plasma deposition. Lab on a Chip, 7(4), 523–525. https://doi.org/10.1039/b615328c
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