The bridge helix coordinates movements of modules in RNA polymerase

18Citations
Citations of this article
40Readers
Mendeley users who have this article in their library.

Abstract

The RNA polymerase 'bridge helix' is a metastable α-helix that spans the leading edge of the enzyme active-site cleft. A new study published in BMC Biology reveals surprising tolerance to helix-disrupting changes in a region previously thought crucial for translocation, and suggests roles for two hinge-like segments of the bridge helix in coordinating modules that move during the nucleotide-addition cycle. © 2010 Hein and Landick; licensee BioMed Central Ltd.

Cite

CITATION STYLE

APA

Hein, P. P., & Landick, R. (2010, November 29). The bridge helix coordinates movements of modules in RNA polymerase. BMC Biology. https://doi.org/10.1186/1741-7007-8-141

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free