Terminating Histone Synthesis to Preserve Centromere Integrity

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Abstract

Histone protein synthesis is activated as cells enter S phase to allow packaging of the newly replicated DNA into chromatin. In this issue of Developmental Cell, Takayama and coworkers elucidate a mechanism for silencing histone expression at the end of S phase in S. pombe. Failure to shut off histone expression disrupts centromeric chromatin structure.

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APA

Marzluff, W. F. (2010, March 16). Terminating Histone Synthesis to Preserve Centromere Integrity. Developmental Cell. Cell Press. https://doi.org/10.1016/j.devcel.2010.03.004

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