Six cases of phaeochromocytoma with unusual clinical manifestations

Abstract

Six cases of phaeochromocytoma are described. In three the picture suggested primary renal disease ; in the others toxaemia of pregnancy, gall-stone colic, and cerebral tumour were initially diagnosed. Weight loss, fever, vomiting, hypotensive episodes, facial plethora, and post-operative oligaemic shock are among other features encountered. Interference with renal function in phaeochromo-cytoma is discussed, and it seems likely that this is due to the high level of circulating vasoconstrictor substances. In one case urinary catechol amine excretion was at first within the normal ranee. Perirenal insufflation with air or carbon dioxide as a means of locating the tumour proved a danger to life in two patients. © 1962, British Medical Journal Publishing Group. All rights reserved.