2,4-Dihydropyrazole glucosides 3a-3c were prepared and tested for their antitumor activity. The structures of these compounds were established by 1H and 13C-NMR spectroscopy. Glucoside 3b shows an in vitro IC50 value of 16.4 μM against proliferation of the human promyelotic leukemia (HL60) cell line.
CITATION STYLE
Abdou, I. M., Saleh, A. M., & Zohdi, H. F. (2004). Synthesis and antitumor activity of 5-trifluoromethyl-2,4-dihydropyrazol-3- one nucleosides. Molecules, 9(3), 109–116. https://doi.org/10.3390/90300109
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