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Effects of orally administered bovine lactoperoxidase on dextran sulfate sodium-induced colitis in mice

Bioscience, Biotechnology and Biochemistry (2008) 72(7) 1932-1935
DOI: 10.1271/bbb.70636
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Abstract

The effect of lactoperoxidase (LPO) on dextran sulfate sodium-induced colitis was examined in mice. After 9 d of colitis induction, weight loss, colon shortening, and the histological score were significantly suppressed in mice orally administered LPO (62.5 mg/body/d) as compared to a group administered bovine serum albumin. These results suggest that LPO exhibits anti-inflammatory effects in the gastrointestinal tract.

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Shin, K., Horigome, A., Yamauchi, K., Takase, M., Yaeshima, T., & Iwatsuki, K. (2008). Effects of orally administered bovine lactoperoxidase on dextran sulfate sodium-induced colitis in mice. Bioscience, Biotechnology and Biochemistry, 72(7), 1932–1935. https://doi.org/10.1271/bbb.70636

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