Reevaluation of the prevalence of metabolic syndrome in an urban area of Turkey

Abstract

Objective: Our aim was to reveal a change in the prevalence of metabolic syndrome (MS) in the province of Konya in five years. Methods: We studied 202 obese children and adolescents (body mass index >95th percentile) aged between 7 and 18 years. The diagnosis of impaired glucose tolerance, type 2 diabetes mellitus (T2DM), and MS were defined according to the modified World Health Organization criteria adapted for children. Results: MS was found in 56.4% with a significantly higher rate among adolescents aged 12-18 years (63.2%) than among prepubertal children aged 7-11 years (47%) (p=0.01). The prevalence figures for insulin resistance, glucose intolerance, and T2DM were 60, 8, and 2% among prepubertal children and 81.8, 12.8, and 0% among adolescents, respectively. The prevalence of fasting hyperinsulinemia in adolescents was significantly higher than in prepubertal children (p<0.001). Hypertension was significantly more common in adolescents (42.8%) than in prepubertal children (32.9%) (p=0.04). Conclusions: We found that the incidence of MS in the city center of Konya approximately doubled in the last five years with increased rates of morbidity and abnormal lipid profiles. © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing.