Diethylnitrosamine (DEN) promoted by carbon tetrachloride (CCl4) forms DNA adducts inducing hepatocellular carcinoma (HCC). Plant alkaloid, harmalol, is being used as a therapeutic agent against HCC due to its accessibility and efficacy by apoptosis and inhibiting proliferation of cancer epithelial cells.
CITATION STYLE
Sarkar, S., Bhattacharjee, P., Ghosh, T., & Bhadra, K. (2020). Pharmaceutical efficacy of harmalol in inhibiting hepatocellular carcinoma. Future Journal of Pharmaceutical Sciences, 6(1). https://doi.org/10.1186/s43094-020-00045-x
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