Abstract
The importance of the HLA-DR locus to multiple sclerosis (MS) susceptibility was assessed in 542 sib pairs with MS and in their families. By genotyping 1,978 individuals for HLA-DRB1 alleles, we confirmed the well-established association of MS with HLA-DRB1*15 (HLA-DRB1*1501 and HLA-DRB5*0101), by the transmission/disequilibrium test (χ2 = 138.3; P
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CITATION STYLE
APA
Ligers, A., Dyment, D. A., Willer, C. J., Sadovnick, A. D., Ebers, G., Risch, N., … Stefanelli, M. (2001). Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis. American Journal of Human Genetics, 69(4), 900–903. https://doi.org/10.1086/323480
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