Evaluation of a new device for quick sutureless coronary artery anastomosis in surviving sheep

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Objective: A new device for performing quick sutureless vascular anastomosis by means of stent technology has recently been developed by Jomed International, Helsingborg, Sweden. The efficacy of this GraftConnector was studied in a sheep model. Methods: In adult sheep, a left anterior thoracotomy under the fourth rib extended across the sternum gave good access to the left anterior descending branch (LAD) and the right internal mammary artery (RIMA). On beating hearts, the GraftConnector group had the RIMA connected to the LAD by means of the new device, while the control animals had the same anastomoses sutured with continuous 7-0 polypropylene sutures. The time for completing the anastomosis (ischemic time) was recorded and the blood flow in the RIMA was recorded with the proximal LAD open and closed, respectively. An intra-operative fluoroscopy with contrast injection directly into the graft was done. Finally the proximal LAD was ligated. The surviving animals are to be followed up. Results: Seven (46%) of the 15 animals operated on with the traditional suturing technique and seven (63%) of the 11 GraftConnector sheep survived the procedures and are to be followed up. The 11 anastomoses done with the GraftConnector were completed in 2.41�0.2 min, and the 14 anastomoses sutured with continuous suture were completed in 6.93�0.419 min (P<0.0001). The RIMA blood-flows in the two groups were comparable and are presented. All the surviving animals had open anastomoses at fluoroscopy. Conclusions: Quick coronary artery anastomoses without suturing on beating hearts can be completed with the new GraftConnector. The GraftConnector creates reproducible anastomoses in much less time than suturing, the per-operative mortality in the GraftConnector Group was accordingly lower. Long-time follow-up of the patency in surviving animals is pending. The presented device may ultimately permit quick anastomoses endoscopically. Copyright (C) 2000 Elsevier Science B.V. © Oxford University Press 2001.




Solem, J. O., Boumzebra, D., Al-Buraiki, J., Nakeeb, S., Rafeh, W., & Al-Halees, Z. (2000). Evaluation of a new device for quick sutureless coronary artery anastomosis in surviving sheep. European Journal of Cardio-Thoracic Surgery, 17(3), 312–318. https://doi.org/10.1016/S1010-7940(99)00357-7

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