The Integruppo Italiano Linfomi (IIL) carried out a study to assess the outcomes of splenic marginal zone lymphoma and to identify prognostic factors in 309 patients. The 5-year cause-specific survival (CSS) rate was 76%. In univariate analysis, the parameters predictive of shorter CSS were hemoglobin levels below 12 g/dL (P < .001), lactate dehydrogenase (LDH) levels above normal (P
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Arcaini, L., Lazzarino, M., Colombo, N., Burcheri, S., Boveri, E., Paulli, M., … Iannitto, E. (2006). Splenic marginal zone lymphoma: A prognostic model for clinical use. Blood, 107(12), 4643–4649. https://doi.org/10.1182/blood-2005-11-4659
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