A access in treatment of type II diabetes using combinational herbal compounds

Abstract

— Diabetes is the common disorder found in case of metabolic disfunction leads to high blood glucose level in our body. Type two polygenic diseases are that the most typical type of polygenic disease. If we have type 2 diabetes our body does not use insulin properly. This is called insulin resistance. At first, our pancreas makes extra insulin to make up for it. But, over time it's not able to carry on and cannot create enough internal secretion to stay your blood sugar at traditional levels. In order to cure Type II diabetes we have identified the gene responsible for the insulin resistance gene from the genomic information resource database. The gene is further analysed and docked with the four herbal components and checked its minimum energy value for further studies. This will be the combination drug and using Nano medicine which will be the target drug delivery towards the target gene which stimulates the activity of the insulin resistant gene. Since its targets towards the gene it will be considered as the gene therapy and new combinatorial medicine, here Bioinformatics, combinatorial chemistry, pharmacology, Nano medicine play a vital role in treatment of diabetes. Type II diabetes is the high risk of day to day life, so considering these facts the gene responsible for diabetes is identified and diagnosis of DNA is done used molecular techniques and mutated gene is identified for further treatment. In this project suitable drug targets is identified and targeted towards the type II diabetes.