Alteration in serum lipid profile levels in Iraqi women with breast cancer before and after chemotherapy

Abstract

Objective: Investigating the role of alterations in lipid profile in Iraqi women with breast cancer before and after chemotherapy. Methods: A total number of 100 patients aged 25–47 years were enrolled in this study, including 35 breast cancer treatment patients, 30 treatment patients, and 10 and 25 healthy women benefactor. All samples were collected from August 2016 to February 2017 from Oncology Hospital/Medical city in Baghdad; however, control group samples were collected from outside the hospital. Serum total cholesterol, serum triglyceride, and serum high-density lipoprotein cholesterol (HDL-C) were measured by spectrophotometer using a kit provided by Linear Chemicals. Results: The results show a highly significant increment (p˂0.01) in lipid profile in breast cancer, especially in diagnosis group as compared with other groups. Conclusion: The alteration in cholesterol, triglyceride, HDL-C, and very low-density lipoprotein is highly connected with breast cancer in Iraqi women, progression of disease and treatment effect.