Neutron induced break‐points in human chromosomes have a similar location as X‐ray induced break‐points

Abstract

The distribution of chromosome breakage points in human chromosomes was studies in lymphocytes irradiated in the G0‐period with fast neutrons. With the G‐banding technique the break points were located in the pale bands, in agreement with the observation in X‐irradiated chromosomes. When lymphocytes from the same donor were used, the individual chromosomes were found to participate in chromosome interchanges in the same non‐random way as after X‐irradiation. The results also indicate that for different donors different chromosomes are more susceptible to neutron‐induced chromosome breakage. © 1978 Mendelian Society of Lund