Randomised trial of telephone intervention in chronic heart failure: DIAL trial

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Abstract

Objective To determine whether a centralised telephone intervention reduces the incidence of death or admissions for worsening heart failure in outpatients with chronic heart failure. Design Multicentre randomised controlled trial. Setting 51 centres in Argentina (public and private hospitals and ambulatory settings). Participants 1518 outpatients with stable chronic heart failure and optimal drug treatment randomised, stratified by attending cardiologist, to telephone intervention or usual care. Intervention Education, counselling, and monitoring by nurses through frequent telephone follow-up in addition to usual care, delivered from a single centre. Main outcome measure All cause mortality or admission to hospital for worsening heart failure. Results Complete follow-up was available in 99.5% of patients. The 758 patients in the usual care group were more likely to be admitted for worsening heart failure or to die (235 events, 31%) than the 760 patients who received the telephone intervention (200 events, 26.3%) (relative risk reduction = 20%, 95% confidence interval 3 to 34, P = 0.026). This benefit was mostly due to a significant reduction in admissions for heart failure (relative risk reduction = 29%, P = 0.005). Mortality was similar in both groups. At the end of the study the intervention group had a better quality of life than the usual care group (mean total score on Minnesota living with heart failure questionnaire 30.6 v 35, P = 0.001). Conclusions This simple, centralised heart failure programme was effective in reducing the primary end point through a significant reduction in admissions to hospital for heart failure.

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APA

Grancelli, H. (2005). Randomised trial of telephone intervention in chronic heart failure: DIAL trial. British Medical Journal, 331(7514), 425–427. https://doi.org/10.1136/bmj.38516.398067.E0

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