Abstract
Sixteen lanostane-type triterpeneoids were isolated from the fruiting bodies of wild Ganoderma lucidum and G. multipileum. The new structures 3S,24S,25,26-tetrahydroxy-5α-lanost-8-en-11-one (1) and ganodermanondiol 24,25-acetonide (10) were elucidated by means of spectroscopic data and Mosher's experiments. Lanosta-7,9(11)-dien-3β-ol (9) strongly inhibited α-glucosidase with the IC50 values of 198.8 μM in compared with acarbose (IC50 712.4 μM).
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Binh, P. T., Thao, N. P., Luyen, N. T., Trang, D. T., Binh, P. T. X., Nguyen, N. P. D., … Dat, N. T. (2018). Lanostane-type triterpenoids from ganoderma lucidum and G. multipileum fruiting bodies. Natural Product Communications, 13(11), 1441–1444. https://doi.org/10.1177/1934578x1801301107
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