Abstract
Creutzfeldt-Jakob disease (CJD) is a brain disorder that causes dementia. It forms part of a set of animal and human diseases called prion disorders. Symptoms of Creutzfeldt-Jakob disease can resemble those of Alzheimer's disease. This disease is always fatal, and most patients do not survive beyond a year. Myoclonus, vision problems, brain and pyramidal/extrapyramidal symptoms, and changes in cognitive function and cognitive abilities are seen as manifestations. We present a case of a 65-year-old woman complaining of rapidly progressive dementia, which was followed by the slowness of movements and inability to speak for 3 months. The patient's family reported jerking of limbs, which was sudden on onset. This case report highlights the differential diagnosis of CJD, which can range from auto-immune diseases, infections, neurodegenerative disorders, metabolic and septic encephalopathies, toxins, ischemia, and drug-induced causes. It helps us to identify and exclude any treatable cause early in the diagnostic process.
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Negandhi, P., Andhale, A., Acharya, S., Khan, F., & Patil, T. (2025). Creutzfeldt-Jakob disease-A case report. International Journal of Nutrition, Pharmacology, Neurological Diseases, 15(1), 112–117. https://doi.org/10.4103/ijnpnd.ijnpnd_154_24
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