Management of Crohn's disease

Abstract

Morbidity from Crohn's disease can be lessened by meticulous specialist management. New techniques for clarifying the site of disease, activity, and complications include scanning with radiolabelled leucocytes, ultrasound, computed tomography, and magnetic resonance imaging. Budesonide, high dose mesalazine and, for refractory disease, methotrexate and antitumour necrosis factor α antibody are new therapeutic options. Other new therapeutic possibilities include a liquid formula diet, endoscopic stricture dilatation, and laparoscopic surgery. The most effective measure for maintenance of remission is stopping smoking. Patients should participate in decisions about their treatment.