Polimerik nanopartikuler ilaç taşıyıcı sistemlerde yüzey modifikasyonu

Abstract

Surface modification can be defined as the improvement and replacement of the surface properties of nano-sized drug delivery systems. In the field of pharmaceutical technology, surface modification provides several advantages to improve the physicochemical properties and pharmaceutical activities of many nanosized carriers particularly polymeric nanoparticles. The surface properties of the polymeric nanoparticulate drug delivery systems play a key role on the biological behaviour that is shown in the organism. By the modification of the surface properties of these systems, targeting potential and cellular uptake levels are increased, blood