An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime

Abstract

In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging. © 2014 The Royal Society of Chemistry.