Paracetamol Research and New Formulation Design

Abstract

Acetaminophen, also known as paracetamol, is the main metabolite of phenacetin and is a derivative of acetanilide. It is a commonly used antipyretic and analgesic drug. Acetaminophen is rapidly and completely absorbed orally in body fluids Evenly distributed in the medium, but inappropriate doses can lead to serious side effects - liver toxicity. With the development of technology, 3D printing technology shows great potential in personalized drug delivery. It can not only print medicines with different doses quickly and conveniently, but also design integrated tablets with multiple independent release mechanisms according to the needs of patients. This paper aims to use 3D printing technology to solve the problem of side effects caused by individual differences, so as to prepare safe, effective and personalized pharmaceutical preparations.