Immunology: Oxysterols hold T cells in check

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Abstract

The oxysterol-dependent gene transcription factor LXRβ restricts premature expansion of T cells by limiting cellular cholesterol levels. This pathway might be a pharmacological target for regulating immune responses. © 2008 Macmillan Publishers Limited. All rights reserved.

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Glass, C. K., & Saijo, K. (2008, September 4). Immunology: Oxysterols hold T cells in check. Nature. Nature Publishing Group. https://doi.org/10.1038/455040a

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