Clinical, laboratory and radiological parameters in children with dengue fever and predictive factors for dengue shock syndrome

Abstract

This article is a prospective study of the clinical, laboratory and radiological picture of children satisfying the case definition criteria of dengue by WHO admitted at Sri Ramachandra Medical College and Research Institute, a suburban tertiary referral centre, to determine the predictive factors for dengue shock syndrome (DSS). Data were analyzed by Chi-squared test and Student's t -test for significance after dividing the patients into two groups, those with and those without DSS for the same. Bleeding manifestations, presence of effusion on USG/X-ray, haematocrit >35%, WBC <4000/cumm, Na ≤ 130 meq/ l, bicarbonate level of ≤ 18 mmol/l, deranged coagulation profile and serum glutamic pyruvic transaminase (SGPT) ≥ 40 IU were predictive of DSS. © 2007 © The Author [2007]. Published by Oxford University Press. All rights reserved.