Edad máxima en la que una mujer puede ser madre con sus propios óvulos: Revisión sistemática

Abstract

Background: The broad use of oocyte donation cycles has resulted in high rates of pregnancy and child birth in women of different ages, including postmenopausal women. This has generated controversy and ethical challenges, motivating many centers to limit the maximum age of oocytes recipients. Aims: To seek a biological and objective criteria to define such maximal age, in which a woman is able to achieve a spontaneous pregnancy and give a birth. Methods: We performed a broad search PUBMED and MEDLINE including articles that reported women who conceived after age40 years and specify the age at last birth, excluding those who received donated eggs. Results: Only two articles presented the inclusion criteria and no exclusion. The maximum reported ages were 49 and 52 years respectively. Conclusion: The maximum age reported in the literature in which a woman has achieved a spontaneous pregnancy and birth with her own gametes is at 52 years.