Synthesis, Characterization and Antibacterial Activity of a Tridentate Schiff Base Derived from Cephalexin and 1,6-Hexanediamine and its Transition Metal Complexes

Abstract

Background: The wide use of the antibiotics resulted in the serious medical problem of drugs resistance and public health concern. Preparation of new synthetic derivatives of antibiotics with novel mechanism of action has become an important task to cope with drug resistance problems.