Hematological and immunological profile of ART-Naïve HIV-infected patients in Bali-Indonesia: A descriptive study

Abstract

HIV infection often comes with hematological and immunological profile abnormalities. These abnormalities may occurred because of HIV infection itself or other factors. Therefore we conducted this study to assess the hematological and immunological profile among ART-naïve HIV-infected patients in Bali. This is a descriptive cross-sectional study using data extracted from medical records of HIV-infected patients at Wangaya Hospital Denpasar-Bali and Sanjiwani Hospital Gianyar-Bali. A total of 169 medical records of HIV infected patients between 2009-2017 were included in this study. Hematological parameters (total WBC, RBC, Hgb, MCV, MCH, MCHC, and Plt) and immunological parameter (CD4+ cell count) were documented. Most of the subjects in this study were male (65.1%) and predominantly (71%) in highly reproductive age group (18-40 years). Anemia (Hb < 13.0 g/dL for men or Hb < 12.0 g/dL for women) was the most common (60.4%) haematological abnormalities seen in this study and 67.4% in severe immunodeficiency condition (CD4 cell count < 200 cells/mm3). Statistical analyses performed and the result shows there was an association between anemia and immunodeficiency status (p < 0.05, Pearson Chi-square).