CPT1A‐IL‐10‐mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury

  • Wang M
  • Wu D
  • Liao X
  • et al.
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Abstract

Graphical Abstract • CPT1A modulated metabolic alteration and polarisation of macrophage under LPS stimulation. • The protective effects of CPT1A may be partly attributed to the induction of interleukin-10/interleukin-10 receptor expression. • The CPT1A-IL-10 axis and its regulated macrophage immunometabolism may provide a novel potential therapeutic targeting of ALI/ARDS. Clin. Transl. Med. 2024;14:e1785. wileyonlinelibrary.com/journal/ctm2 https://doi.

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Wang, M., Wu, D., Liao, X., Hu, H., Gao, J., Meng, L., … Gao, W. (2024). CPT1A‐IL‐10‐mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury. Clinical and Translational Medicine, 14(8). https://doi.org/10.1002/ctm2.1785

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