A facile one-pot solvent-free synthesis of 1,2-dihydro-1-arylnaphtho[1,2-e] [1,3]oxazine-3-ones catalyzed by wet cyanuric chloride

Abstract

A novel one-pot synthesis of 1,2-dihydro-1-arylnaphtho[1,2-e][1,3]oxazine- 3-ones by condensation of a variety of aldehydes with β-naphthol and urea or thiourea in the presence of wet cyanuric chloride under solvent-free condition has been described. High yields, simple procedure, easy workup, short reaction times, and avoiding the use of organic solvent are the advantages of this green methodology. © 2013 Firouzeh Nemati and Azam Beyzai.